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An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

机译：造血干细胞衰老的表观遗传成分，可以重新编程为年轻状态。

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摘要

Key points Hematopoietic stem cell aging associate with stable transcriptional alterations that persist through transplantation.Somatic cell reprogramming of aged hematopoietic stem and progenitor cells reverses functional defects associated with hematopoietic aging.

机译：要点造血干细胞衰老与通过移植持续存在的稳定转录改变相关。衰老的造血干细胞和祖细胞的体细胞重编程逆转了与造血衰老相关的功能缺陷。

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作者
Wahlestedt, Martin; Norddahl, Gudmundur; Sten, Gerd; Ugale, Amol; Micha Frisk, Mary-Ann; Mattsson, Ragnar; Deierborg, Tomas; Sigvardsson, Mikael; Bryder, David;
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年度 2013
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正文语种 eng
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1. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. [J] . Martin Wahlestedt, Gudmundur L Norddahl, Gerd Sten, Blood: The Journal of the American Society of Hematology . 2013,第21期

机译：造血干细胞衰老的表观遗传成分，可重新编程为年轻状态。
2. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. [J] . Martin Wahlestedt, Gudmundur L Norddahl, Gerd Sten, Blood: The Journal of the American Society of Hematology . 2013,第21期

机译：造血干细胞衰老的表观遗传成分，可重新编程为年轻状态。
3. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. [J] . Martin Wahlestedt, Gudmundur L Norddahl, Gerd Sten, Blood: The Journal of the American Society of Hematology . 2013,第21期

机译：造血干细胞老化的表观遗传成分，致力于重编程成年轻状态。
4. Selection and Preparation of the Multi-component Cryoprotectant Agent for Vitrification of Hematopoietic Stem/Progenitor Cells Derived from Human Umbilical Cord Blood [C] . Zeljka Bosnjak, rnFrederic Daigne, rnGuillatume Dubus Asian Pacific Confederation of Chemical Engineering congress . 2008

机译：用于人脐带血造血干/祖细胞玻璃化的多组分抗冻剂的选择与制备
5. Widespread Epigenetic Reprogramming in Aging Human Hematopoietic Stem Cells [D] . Adelman, Emmalee R. 2018

机译：人类造血干细胞老化中的广泛表观遗传重编程。
6. Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming [O] . Srijaya Thekkeparambil Chandrabose, Sandhya Sriram, Subha Subramanian, 2018

机译：牙髓干细胞的适宜表观遗传特性是无异源游离体重编程的高能力
7. Epigenetic plasticity of chromatin in embryonic and hematopoietic stem/progenitor cells: therapeutic potential of cell reprogramming [O] . ZARDO G, G. CIMINO, NERVI C 2008

机译：染色质在胚胎和造血干/祖细胞中的表观遗传可塑性：细胞重编程的治疗潜力

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

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